The link between cord blood IL-1β, TLR4, PGE2 and TAC values with neonatal diseases

Premature birth is an important cause of neonatal mortality and morbidity. Most premature births are known to be induced by cytokines released for different reasons. Inadequate congenital immune response in infants may contribute increased susceptibility infection. The aim the study determine IL-1β, TLR4, PGE2, TAC profiles cord blood with characteristics specific pregnancy correlation complications caused birth. included 26 neonates, 11 girls 15 boys, born from 24-42 weeks gestation. Of these, 13 were term preterm . For IL-β, PG-E2, TLR4 levels, 1 mL sample was taken neonates. Data related demographic data, clinical status patients outcomes obtained electronic medical records files. Cytokine values neonates statistically high terms IL1 PGE2 compared infants. TRL4 necrotizing enterocolitis retinopathy prematurity lower those without NEC ROP. In spite negative correlations between other three cytokines, a significant not identified. negatively correlated weight gestational week, contrarily measurements positively week. Measurements cytokine concentrations among biomarkers showing degree inflammation assist predicting play effective role development treatments.